Copper-64 radiolabeling and biological evaluation of bifunctional chelators for radiopharmaceutical development
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چکیده
منابع مشابه
Maleimido-functionalized NOTA derivatives as bifunctional chelators for site-specific radiolabeling.
Two basic and simple synthetic routes for mono- and bis-maleimide bearing 1,4,7-triazacyclononane-N,N',N''-triacetic acid (NOTA) chelators as new bifunctional chelators are described. The syntheses are characterized by their simplicity and short reaction times, as well as practical purification methods and acceptable to very good chemical yields. The usefulness of these two synthetic pathways i...
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The chemical modification of oligomers such as DNA, PNA, MORF, LNA to attach radionuclides for nuclear imaging and radiotherapy applications has become a field rich in innovation as older methods are improved and new methods are introduced. This review intends to provide a brief overview of several chelators currently in use for the labeling of oligomers with metallic radionuclides such as 99m ...
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ژورنال
عنوان ژورنال: Nuclear Medicine and Biology
سال: 2012
ISSN: 0969-8051
DOI: 10.1016/j.nucmedbio.2012.05.009